Even after spending weeks writing the original plans for 1SubML, there were a number of unresolved issues, and many more changes required by issues I ran into during development. On the one hand, it’s an illustration of “no plan survives contact with the enemy”, but on the other hand, the final version of 1SubML is still basically the same as the original vision, and I managed to fulfill all the original goals I had for the language.
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生物学家使用基于Linux的GATK4分析框架（集成Apache Spark的基因组工具包），数据存储在共享NFS服务器。为连接云端，JS开发了名为"bunnies"的系统（又一个繁殖力玩笑），将分析任务封装至容器在S3运行。这显著提升了分析速度、可重复性与并行性能，但存储边界的摩擦问题日益凸显。
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